Leishmania (LPG) Mouse Monoclonal Antibody [Clone ID: CA7AE]

Specifications

Product Data
Clone Name	CA7AE
Applications	ELISA, IF, WB
Recommend Dilution	ELISA: 1/1000. Immunoblotting. Immunofluorescence: 1/500-1/1000.
Reactivity	Leishmania donovani
Host	Mouse
Clonality	Monoclonal
Immunogen	Heat killed Leishmania donovani promastigotes.
Specificity	AM01175SU-N is specific for Lipophosphoglycan (LPG) the major cell surface glycoconjugate of Leishmania parasites. AM01175SU-N recognizes the repeat carbohydrate epitope of most species of Leishmania LPG. The epitope is also found on the excreted acid phosphatase of Leishmania.
Formulation	State: Ascites State: Lyophilized Ascites Stabilizer: None Preservative: None
Reconstitution Method	Restore with 0.5 ml distilled sterile water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Leishmania is a genus of trypanosome protozoa, and is the parasite responsible for the disease leishmaniasis. It is spread through sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World. Their primary hosts are vertebrates; Leishmania commonly infects hyraxes, canids, rodents, and humans. Leishmania currently affects 12 million people in 88 countries. An important determinant of Leishmania infectivity and survival in the mammalian host is the surface macromolecule - lipophosphoglycan or LPG. This is the major macromolecule on the surface of Leishmania. LPG consists of a polymer of phosphorylated dissaccharide repeat units attached by a polysaccharide core to a novel lipid anchor.
Reference Data

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