CD21 (CR2) Mouse Monoclonal Antibody [Clone ID: LT21]

CAT#: AM03064PU-N

CD21 (CR2) mouse monoclonal antibody, clone LT21, Purified

Conjugation: Unconjugated FITC PE



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CNY 3,140.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name LT21
Applications FC, IHC
Recommend Dilution Flow cytometry: Recommended dilution: 1-5 μg/ml.
Reactivity Bovine, Canine, Human, Porcine
Host Mouse
Clonality Monoclonal
Immunogen IM9 human B-lymphoblastoid cell line
Specificity The antibody LT21 reacts with CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
Formulation PBS, pH 7.4 containing 15 mM sodium azide as preservative
State: Purified
State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE)
Concentration lot specific
Purification Purified by protein-A affinity chromatography.
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name complement component 3d receptor 2
Background CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Synonyms Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic Cell Marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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