c-Myc (MYC) Mouse Monoclonal Antibody [Clone ID: 33]

Specifications

Product Data
Clone Name	33
Applications	IHC, IP, WB
Recommend Dilution	Western Blot. Immunoprecipitation (both with and without SDS). Immunohistochemistry on Frozen Sections. Myc is a labile protein, therefore preotease inhibitors should be used at all times.
Reactivity	Human, Mouse, Rat, Birds
Host	Mouse
Clonality	Monoclonal
Immunogen	Hybridoma produced by the fusion of splenocytes from mice immunized
Formulation	PBS containing 0.08% Sodium Azide as preservative. State: Purified State: Liquid (0.2 µm sterile filtered) purified IgG fraction.
Concentration	lot specific
Purification	From ascites.
Conjugation	Unconjugated
Storage Condition	Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	v-myc avian myelocytomatosis viral oncogene homolog
Database Link	Entrez Gene 4609 Human UniProt ID P01106
Background	Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64 kDa and 67 kDa, the unphosphorylated form is 49 kDa.
Synonyms	Transcription factor p64, BHLHE39
Reference Data

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