SNAP25 Mouse Monoclonal Antibody [Clone ID: S-7B8]

Specifications

Product Data
Clone Name	S-7B8
Applications	IHC, WB
Recommend Dilution	Western blot (1-5 µg/ml). Immunohistochemistry on Paraformaldehyde fixed CNS tissues (1-5 µg/ml). Does not stain reduced proteins. Positive Control: Cerebellum.
Reactivity	Bovine, Chicken, Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat brain synaptosomal membranes and mouse NS1 cells.
Formulation	PBS containing 0.08% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	synaptosome associated protein 25kDa
Database Link	Entrez Gene 6616 Human UniProt ID P60880
Background	SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells. These two isoforms differ by 9 amino acids in the central portion of the protein.
Synonyms	SNAP-25, SUP, SNAP, Super Protein, RIC4, ric-4
Reference Data

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