Mycobacterium tuberculosis (38 kDa antigen) Mouse Monoclonal Antibody [Clone ID: BGN/1209/3875]

Specifications

Product Data
Clone Name	BGN/1209/3875
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Mycobacterium tuberculosis
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant 38 kDa antigen from Mycobacterium tuberculosis
Specificity	This antibody recognises the 38 kDa antigen from Mycobacterium tuberculosis, a peptide believed to be involved in the regulation of proteins necessary for virulence.
Formulation	PBS containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
Synonyms	M. tuberculosis, TB
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.