Glucose 6 phosphate isomerase (GPI) Mouse Monoclonal Antibody [Clone ID: 1B7D7]

Specifications

Product Data
Clone Name	1B7D7
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA: 1/10000.  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000.  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human GPI expressed in E. Coli.
Specificity	Recognizes Glucose-6-phosphate isomerase
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glucose-6-phosphate isomerase
Database Link	Entrez Gene 2821 Human UniProt ID P06744
Background	Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Synonyms	Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Neuroleukin, NLK
Reference Data

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