REG1 alpha (REG1A) Mouse Monoclonal Antibody [Clone ID: 1A4]

Specifications

Product Data
Clone Name	1A4
Applications	ELISA, IF, IHC
Recommend Dilution	ELISA: 1/10000. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human REG1A fused with hIgGFc tag expressed in HEK293 cell line.
Specificity	Recognizes REG1A (regenerating islet-derived 1 alpha)
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	19 kDa
Gene Name	regenerating family member 1 alpha
Database Link	Entrez Gene 5967 Human UniProt ID P05451
Background	REG1A (regenerating islet-derived 1 alpha), also known as PTP, PSP, is a member of the Reg family of secreted proteins with a C-type lectin domain. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis.Due to variable glycosylation, pancreatic REG1A exists as multiple species of 16 - 18 kDa. REG1A promotes the maintenance and growth of pancreatic islet β-cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. REG1A is an antigenic target in autoimmune diabetes.
Synonyms	REG1A, PSPS, REG, Lithostathine-1-alpha, Pancreatic stone protein, PSP, Pancreatic thread protein, PTP, Islet of Langerhans regenerating protein, Regenerating protein I alpha, Islet cells regeneration factor, ICRF
Reference Data

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