MEK6 (MAP2K6) Mouse Monoclonal Antibody [Clone ID: 3H12C8]

Specifications

Product Data
Clone Name	3H12C8
Applications	ELISA, FC, IF, WB
Recommend Dilution	ELISA: 1/10000.  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human MAP2K6 expressed in E. Coli.
Specificity	Recognizes MAP2K6
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	38 kDa
Gene Name	mitogen-activated protein kinase kinase 6
Database Link	Entrez Gene 5608 Human UniProt ID P52564
Background	This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas .
Synonyms	MAPKK 6, MAPK/ERK kinase 6, SAPKK3, MEK6, MKK6, MAP kinase kinase 6
Reference Data

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