HIF-1 alpha (HIF1A) Mouse Monoclonal Antibody [Clone ID: 1A3]

CAT#: AM06608SU-N

HIF-1 alpha (HIF1A) mouse monoclonal antibody, clone 1A3, Ascites



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CNY 5,775.00


货期*
5周

规格
    • 100 ul

Cited in 2 publications.

Product images

Specifications

Product Data
Clone Name 1A3
Applications ELISA, IF, IHC, WB
Recommend Dilution ELISA: 1/10000.
Western Blot: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000. 
Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity Human, Monkey, Mouse
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of Human HIF1A expressed in E. Coli.
Specificity Recognizes HIF1 alpha (HIF1A)
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size 120 kDa
Gene Name hypoxia inducible factor 1 alpha subunit
Background Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors.
Synonyms HIF-1 alpha, Hypoxia-inducible factor 1 alpha, ARNT-interacting protein, Member of PAS protein 1, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

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