Ly6c1 Rat Monoclonal Antibody [Clone ID: HK1.4]

Specifications

Product Data
Clone Name	HK1.4
Applications	FC, FN, IHC
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2) Immunohistochemistry on Frozen Sections. (Ref.5) In vitro Activation of T Lymphocytes. (Ref.1,2)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody is specific to Murine Ly-6C (Mr. 18 kDa)
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lymphocyte antigen 6 complex, locus C1
Database Link	Entrez Gene 17067 Mouse UniProt ID P0CW02
Background	Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes. (Ref.1-4)
Synonyms	Lymphocyte antigen 6C2, Ly-6C2, Ly6C2, Mouse Macrophage Marker
Reference Data

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