Cytokeratin 18 (KRT18) (N-term) Mouse Monoclonal Antibody [Clone ID: SB38b]

CAT#: AM08175PU-N

Cytokeratin 18 (KRT18) (N-term) mouse monoclonal antibody, clone SB38b, Purified



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CNY 4,026.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name SB38b
Applications ELISA, IHC, WB
Recommend Dilution ELISA: 1/5,000-1/20,000.
Western Blot: 1/2,000-1/4,000.
Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections): 10 µg/ml
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant N-terminal fragment of keratin 18.
Specificity This antibody reacts specifically specifically with Keratin 18 and recombinant N-terminal Keratin 18.
Formulation 100 mM Borate buffered saline, pH 8.0 without preservatives or amine-containing buffer salts.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Gene Name keratin 18
Background Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8). The two keratin types share only 30% sequence homology. (Ref.1-6) Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein of approximately 48 kDa. It exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia, and is often co-expressed with cytokeratin 8. (Ref.6-8) Tissues from the gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Synonyms Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18
Note Chatacterization: To ensure acceptable performance, each batch of product is tested by ELISA, Immunohistochemical staining (HT29 and HCC38 cells) and Western blotting (HT29 and HCC38 cell lysates) to conform to characteristics of a standard reference reagent.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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