BAFF (TNFSF13B) Mouse Monoclonal Antibody [Clone ID: T7-241]

CAT#: AM08333PU-N

BAFF (TNFSF13B) mouse monoclonal antibody, clone T7-241, Aff - Purified



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CNY 5,654.00


货期*
5周

规格
    • 50 ug

Product images

Specifications

Product Data
Clone Name T7-241
Applications ELISA, FC, IHC
Recommend Dilution ELISA.
Flow Cytometry.
Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human BAFF(TL7) protein
Specificity This antibody ecognizes CD257/BAFF.
Formulation PBS, pH 7.2 containing 0.09% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity Chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name tumor necrosis factor superfamily member 13b
Background Members of the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL1 (for TNF- and ApoL- related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NFkB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF also signals through a third TNF receptor BAFFR/BR3. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNFa and TRAIL, THANK was shown to activate NF-kB and c-jun N terminal kinase (JNK) and to induce apoptosis.
The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain.
Synonyms TNFSF13B, BLYS, TALL1, TNFSF20, ZTNF4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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