CD59 Mouse Monoclonal Antibody [Clone ID: p282 (H19)]

Specifications

Product Data
Clone Name	p282 (H19)
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: 2 µg/10E6 cells. Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity	Human, Monkey, Chimpanzee, Baboon
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes CD59 Glycoprotein.
Formulation	PBS, pH 7.2 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	CD59 molecule
Database Link	Entrez Gene 966 Human UniProt ID P13987
Background	CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Synonyms	MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21, MACIF, MAC-IP, MIRL, HRF20, HRF-20
Reference Data

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