Factor VII (F7) Mouse Monoclonal Antibody [Clone ID: RFFVII/2]

Specifications

Product Data
Clone Name	RFFVII/2
Applications	ELISA, R, WB
Recommend Dilution	ELISA. Clone RFFVII/2 may be used as a Capture antibody in Immunoassay for Factor VII in combination with clone RFFVII/1 as a Detection reagent. Radioimmunoassays. Western blotting: This Factor VII antibody binds to a conformational epitope and will not bind to reduced Factor VI.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Factor VII.
Specificity	Recognizes Human Factor VII antigen. Other spcies not tested.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative State: Aff - Purified State: Liquid purified IgG fraction from Tissue Culture Supernatant
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	coagulation factor VII
Database Link	Entrez Gene 2155 Human UniProt ID P08709
Background	Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having anormal circulating concentration of between 400 and 600 µg/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts Prothrombin to Thrombin.
Synonyms	Proconvertin, SPCA
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Complement and coagulation cascades

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