ornithine aminotransferase (OAT) Mouse Monoclonal Antibody [Clone ID: AT23A2]

Specifications

Product Data
Clone Name	AT23A2
Applications	ELISA, FC, IF, WB
Recommend Dilution	ELISA. Western blot (1/250-1/1000).  Flow Cytometry. Immunofluorescence (1/250-1/500).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human OAT (33-439aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse OAT. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ornithine aminotransferase
Database Link	Entrez Gene 18242 MouseEntrez Gene 4942 Human UniProt ID P04181
Background	OAT is a 49-kDa nucleus-encoded protein imported into mitochondria to give the mature 48-kDa OAT polypeptide. It has been described in humans, animals, insects, plants and microorganisms. Especially OAT have sex-differential expression in the mouse kidney. OAT plays crucial physiological roles in amino acid metabolism. OAT shows a large structural and mechanistic similarity to other enzymes from the subgroup III of aminotransferases, which transfer an amino group from a carbon atom that does not carry a carboxyl function. OAT is essential for nitrogen recycling from arginine but not for the stress-induced proline accumulation.
Synonyms	Ornithine aminotransferase mitochondrial
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Metabolic pathways

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