Complement C9 (C9) Mouse Monoclonal Antibody [Clone ID: X197]

Specifications

Product Data
Clone Name	X197
Applications	ELISA, FN, IHC, WB
Recommend Dilution	Immunohistochemistry on frozen and paraffin sections: The typical starting working dilution is 1:10. Flow cytometry: The typical starting working dilution is 1:10. Immunoassay. Western blot: The typical starting working dilution is 1:10. Functional assay: Inhibits C9 binding to C5b-8.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody detects C9.
Formulation	PBS Label: FITC State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G
Conjugation	FITC
Storage Condition	Store at 2 - 8 °C.
Gene Name	complement component 9
Database Link	Entrez Gene 735 Human UniProt ID P02748
Background	Human C9 is a soluble glycoprotein of 61 kD. It is the last component in the assembly of the membrane attack complex (MAC). When the complement is activated on target membranes, multiple copies of C9 bind to the C5b-8 complex and assemble the barrel-shaped pore which causes cell lysis. The conformation of C9 changes from globular to a tubular form. The binding of C9 to C5b-8 plays a key role in the function of C9.
Synonyms	Complement component C9, Complement 9
Reference Data

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