MEOX 2 (MEOX2) (1-304) Mouse Monoclonal Antibody [Clone ID: 6A5]

Specifications

Product Data
Clone Name	6A5
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Immunofluorescence: 10 µg/ml. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	MEOX2 (AAH17021, 1 a.a. ~ 304 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity	This antibody reacts to MEOX2 at aa 1-304.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	mesenchyme homeobox 2
Database Link	Entrez Gene 17286 MouseEntrez Gene 29279 RatEntrez Gene 4223 Human UniProt ID P50222
Background	Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Synonyms	GAX, MOX2, Growth arrest-specific homeobox, Mesenchyme homeobox 2, Homeobox protein MOX-2
Reference Data
Protein Families	Transcription Factors

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