CD28 Mouse Monoclonal Antibody [Clone ID: B-T3]

Specifications

Product Data
Clone Name	B-T3
Applications	FC, FN, IHC
Recommend Dilution	Flow Cytometry. Immunohistochemistry. Functional Assay: Inhibits Mixed Lymphocyte Culture. Co-stimulates T cell proliferation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	U266 cell line
Specificity	This antibody recognises the B7/BB1 receptor (B7/BB1 R), a 44 kDa protein.
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free. State: Azide Free State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	CD28 molecule
Database Link	Entrez Gene 940 Human UniProt ID P10747
Background	CD28 contains 1 Ig-like V-type (immunoglobulin-like) domain. Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
Synonyms	TP44
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

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