NSE (ENO2) Mouse Monoclonal Antibody [Clone ID: NSE-P2]

Specifications

Product Data
Clone Name	NSE-P2
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot. Immunohistochemistry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Enolase of Human origin.
Specificity	This antibody recognizes Neuron-Specific Enolase (NSE, ENO2).
Formulation	PBS containing 0.02% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	enolase 2
Database Link	Entrez Gene 2026 Human UniProt ID P09104
Background	Neuron-specific enolase 2 (NSE-P2, ENO2, Enolase 2, 2-Phospho-D-Glycerate Hydrolase, gamma neuronal, gamma/gamma) is an 80 kD protein and one of the five isozymes of enolase, a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. Enolase is thought to serve as a growth factor in neurons and is released into the central nervous system when neural tissue is injured. Measurement of NSE levels in patients with neuroblastoma and small lung cancer can give an indication as to the extent of the disease. NSE-P2 is one of three different enolase isozymes found in the human brain.
Synonyms	NSE, ENO2, Enolase 2,Neural enolase, Gamma-enolase
Reference Data
Protein Pathways	Glycolysis / Gluconeogenesis, Metabolic pathways, RNA degradation

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