Uromucoid (UMOD) Mouse Monoclonal Antibody [Clone ID: 10.32]

CAT#: AM31843PU-N

Uromucoid (UMOD) mouse monoclonal antibody, clone 10.32, Purified

Conjugation: Unconjugated FITC HRP



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AM31843PU-N is a possible alternative to BP827.

CNY 6,523.00


货期*
5周

规格
    • 250 ug

Product images

Specifications

Product Data
Clone Name 10.32
Applications ELISA, IF, IHC
Recommend Dilution Immunofluorescence.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Formalin, Fixed, Paraffin Embedded Sections: 20 µg/ml.
It can also be used to purify THP by binding to a solid phase.
Reactivity Canine, Human
Host Mouse
Clonality Monoclonal
Immunogen Human Tamm-Horsfall protein.
Specificity Anti-Human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein.
This monoclonal antibody has shown good localization to the distal tubule and collecting duct as well as to large deposits of Tamm-Horsfall protein which has clogged peri-pelvic veins.
Formulation PBS containing 0.02% Sodium Azide as preservative.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Purification Protein G Chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name uromodulin
Background Tamm-Horsfall Protein (THP) is a glycoprotein of approximately 80 kDa containing up to 25% carbohydrate by weight. It exists as a high molecular weight polymer in urine and approximately 50 mg of the THP are excreted per day by adult humans. THP is produced by the epithelial cells lining the thick ascending loop of Henle and distal convoluted tubules of the kidney. THP is also the primary constituent of renal tubular casts and THP aggregation has been implicated as a factor in the pathogenesis of acute renal failure by causing tubular obstruction. Antibody to THP is present in the serum of patients with pyelonephritis and reflus uropathy.
Synonyms Tamm-Horsfall urinary glycoprotein, THP
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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