alpha Actinin (ACTN1) Mouse Monoclonal Antibody [Clone ID: CB11]

Specifications

Product Data
Clone Name	CB11
Applications	ELISA, IHC, WB
Recommend Dilution	Western blotting: 1/1000.  Immunohistochemical on Frozen Sections.  Other Immunoassays for cellular and tumor biology.
Reactivity	Chicken, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified a-actinin from Chicken gizzard. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Specificity	The antibody clone CB11 is specific to the 100 kD Alpha-Actinin polypeptide and reacts with Human and Chicken cells.
Formulation	PBS State: Ig Fraction State: Liquid Ig fraction Stabilizer: 1.0% BSA Preservative: 0.09% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	actinin alpha 1
Database Link	Entrez Gene 87 Human UniProt ID P12814
Background	Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.
Synonyms	Alpha actinin cytoskeletal isoform, Non-muscle alpha-actinin 1
Reference Data

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