Rat Tumors, epithelial origin Mouse Monoclonal Antibody [Clone ID: MG1]

Specifications

Product Data
Clone Name	MG1
Applications	ELISA, IHC, IP, WB
Recommend Dilution	ELISA.  Western blotting.  Flow Cytometry. Immunoprecipitation.  Immunohistochemistry on Frozen Sections.  Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Tissue: There is some cross reactivity in thymus and lymph nodes. Citric acid or EDTA pre-treatment is recommended.
Reactivity	Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Immunization of mice with Rat colon adenocarcinoma cells (CC531).
Specificity	MG1 is a Rat strain-independent markers for tumour cells of epithelial origin, such as colon, breast, or lung cancer, etc. When injected in colon tumour-bearing rats, MG1 localizes to tumour cells (Hagenaars et al., 2001). This Monoclonal antibody recognizes a cell surface structure of about 80 kD expressed by Rat tumour cells of epithelial origin. It is suitable for in vivo applications as it has no detectable binding to other cell types then tumour cells when injected in Rats. MG1 is also useful for immunohistochemical detection of tumour cells. This Monoclonal antibody clone MG1 belongs to a second generation of antibodies directed against tumours of epithelial origin that were strictly selected for minimal cross reactivity with other tissues.
Formulation	State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for two months or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Common epithelial tumors begin in the surface epithelium of the ovaries and account for about 90% of all ovarian cancers. They are divided into a number of subtypes - including serous, endometrioid, mucinous, and clear cell tumors - that can be further classified as benign (noncancerous) or malignant (cancerous) tumors.
Synonyms	Rat Tumor Marker
Reference Data

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