prothymosin, alpha (PTMA) Mouse Monoclonal Antibody [Clone ID: 4A7]

Specifications

Product Data
Clone Name	4A7
Applications	ELISA, WB
Recommend Dilution	ELISA: This antibody is reactive to recombinant PTMA protein.  Western blot: This antibody is reactive to 38.4KDa GST tagged recombinant PTMA protein.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	A short peptide (eeaengrdapangnan) derived from PTMA was conjugated with KLH for immunization.
Specificity	This antibody is reactive to PTMA peptide (eeaengrdapangnan) and GST tagged recombinant PTMA protein.
Formulation	0.01M PBS, pH 7.0 without preservatives State: Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Concentration	1.0 mg/ml (after reconstitution)
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month  or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	prothymosin, alpha
Database Link	Entrez Gene 5757 Human UniProt ID P06454
Background	PTMA (prothymosin alpha) is the precursor of thymosin α1. It is an acidic, non-histone nuclear protein with 109-111 amino acids. PTMA is implicated with cell cycle regulation, chromatin remodeling, expression of oxidative stress-response genes and immunomodulation. PTMA is elevated in malignances such as breast cancer, gastric cancer, prostate and bladder cancers. PTMA is a potential biomarker for the prognosis of cancer treatment.
Synonyms	PTMA, TMSA, Thymosin alpha-1
Reference Data

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