Apolipoprotein A I (APOA1) (25-267) Mouse Monoclonal Antibody [Clone ID: AT1E12]

Specifications

Product Data
Clone Name	AT1E12
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: (1/500-1/5,000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human APOA1 (25-267aa) purified from E. coli
Specificity	The antibody recognizes Human APOA1. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	apolipoprotein A1
Database Link	Entrez Gene 335 Human UniProt ID P02647
Background	Apolipoprotein A1 (APOA1) is the main protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in APOA1 are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. High level of APOA1 is regarded as protective against atherosclerosis and cardiovascular disease.
Synonyms	APOA1, ApoA-I, Apo-AI, ApoAI
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	PPAR signaling pathway

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