PIG3 (TP53I3) (1-332) Mouse Monoclonal Antibody [Clone ID: AT1C9]

Specifications

Product Data
Clone Name	AT1C9
Applications	ELISA, FC, WB
Recommend Dilution	ELISA. Western blot (1:3,000). Flow cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human TP53I3 (1-332aa) purified from E. coli
Specificity	This antibody detects Recombinant human TP53I3 (1-332aa).
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tumor protein p53 inducible protein 3
Database Link	Entrez Gene 9540 Human UniProt ID Q53FA7
Background	TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.
Synonyms	p53-induced gene 3 protein, PIG3
Reference Data

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