Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: AT1D10]

Specifications

Product Data
Clone Name	AT1D10
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/500-1/5000.  Immunohistochemistry on Paraffin Sections: This Monoclonal antibody is reported to work at 10 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human KLK3 (25-261aa) purified from E. coli
Specificity	This Monoclonal AT1D10 antibody recognizes Human PSA/Prostate Specific Antigen. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	kallikrein related peptidase 3
Database Link	Entrez Gene 354 Human UniProt ID P07288
Background	Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. PSA is now used to indicate the presence of semen in forensic serology. The semen of adult males has PSA levels far in excess of those found in other tissues; therefore, a high level of PSA found in a sample is an indicator that semen may be present. Because PSA is a biomarker that is expressed independently of spermatozoa, it remains useful in identifying semen from vasectomized and azoospermic males.
Synonyms	Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Reference Data

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