BUB3 Mouse Monoclonal Antibody [Clone ID: AT2H6]

CAT#: AM50343PU-N

BUB3 mouse monoclonal antibody, clone AT2H6, Purified

Size: 50 ul 100 ul



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CNY 6,620.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name AT2H6
Applications ELISA, WB
Recommend Dilution The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant human BUB3 (1-328aa) purified from E. coli.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name BUB3, mitotic checkpoint protein
Background BUB3 (budding uninhibited by benzimidazoles 3 homolog) is a conserved component of the mitotic spindle assembly complex (MCC). It contains five WD repeat domains and forms cell cycle constitutive complexes with BUB1 and BUBR1. BUB3 is essential for the kinetochore localization of BUB1 and BUBR1. As a component of the MCC, BUB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. The spindle checkpoint pathway functions to postpone the initiation of anaphase until chromosomes are properly attached to the spindle. This acts to ensure accurate chromosome segregation. In addition, BUB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments.
Synonyms BUB3L; hBUB3
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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