esxA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blotting (Reducing conditions): 0.2-1 μg/ml.
Reactivity	Mycobacterium tuberculosis
Host	Rabbit
Clonality	Polyclonal
Immunogen	EsaT-6 (Rv3875) of Mycobacterium tuberculosis.
Specificity	This polyclonal antibody reacts with EsaT-6, a 11,8 kDa antigen encoded by gene Rv3875 of Mycobacterium tuberculosis. The antibody recognizes EsaT-6 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis. It reacts also with recombinant antigen produced in Escherichia coli.
Formulation	PBS, pH~7.4 State: Aff - Purified State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Database Link	UniProt ID P0A564
Background	The ESAT6 antigen from Mycobacterium tuberculosis is a dominant target for cell mediated immunity in the early phase of tuberculosis (TB) in TB patients as well as in various animal models. ESAT6 is not found in M. bovis BCG. Its function is not known but it elicits high level of IFN-gamma from memory effector cells during the first phase of a protective immune response.
Synonyms	esxA, esaT-6, Rv3875, MT3989, MTV027.10
Reference Data

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