GLP1 (GCG) (N-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human, Porcine
Host	Goat
Clonality	Polyclonal
Immunogen	Porcine glucagon, amino acids 1-12, conjugated with bTG.
Specificity	This antibody recognises the pancreatic polypeptide hormone Glucagon, whose actions are antagonistic to insulin.  Tumours arising from glucagon producing cells are termed glucagonomas, and this antibody may be useful in identifying such tumours.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glucagon
Database Link	Entrez Gene 2641 Human UniProt ID P01275
Background	Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.
Synonyms	GCG
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein

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