RNF34 Rabbit Polyclonal Antibody

CAT#: AP05687PU-N

RNF34 rabbit polyclonal antibody, Purified



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CNY 5,423.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Applications ELISA, WB
Recommend Dilution ELISA: 1800 - 1:4000.
Western Blot: 1:100 - 1:600; detects a band of approximately 42kDa.
Reactivity Bovine, Canine, Human, Mouse, Primate, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein corresponding to amino acids 1-373 of human RFI.
Specificity This antibody detects Ring Finger homologous to Inhibitor of apoptosis protein (hRFI).
Formulation Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3)
State: Purified
State: Liquid purified IgG
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name ring finger protein 34
Background RFI is an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL. It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation. hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm. hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.
Synonyms CARP1, CARP-1, RIFF
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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