beta Catenin (CTNNB1) Rabbit Polyclonal Antibody

CAT#: AP06038PU-S

beta Catenin (CTNNB1) rabbit polyclonal antibody, Aff - Purified

Size: 100 ug 25 ul



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CNY 800.00


货期*
2周

规格
    • 25 ul

Product images

Specifications

Product Data
Applications ELISA, IHC, WB
Recommend Dilution Western blot: 1/500-1/1000.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids N-terminus of Human Catenin-β.
Specificity This antibody detects endogenous levels of Catenin-β protein (region surrounding Ile35).
Formulation Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Predicted Protein Size ~ 92 kDa
Gene Name catenin beta 1
Background The catenins, α, β and γ, are proteins which bind to the highly conserved,intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, is a protein that binds with α-catenin and N-cadherin. It has been shown thatthe transmembrane phosphatase PTPμ associates with catenin/cadherin complexes and may regulate complex signaling.
Synonyms CTNNB1, CTNNB, Beta-catenin
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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