Muscarinic Acetylcholine Receptor M3 (CHRM3) (3rd Cytopl. Dom) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Reactivity	Human, Mouse, Bovine, Bat, Canine, Equine, Hamster, Monkey, Porcine, Rabbit, Rat, Sheep
Host	Rabbit
Clonality	Polyclonal
Immunogen	CHRM3 / M3 antibody was raised against synthetic 16 amino acid peptide from 3rd cytoplasmic domain of Human CHRM3 / M3.
Specificity	This antibody detects 3rd cytoplasmic domain of Human Muscarinic Acetylcholine Receptor M3 (CHRM3).  BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
Formulation	PBS containing 0.09% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cholinergic receptor muscarinic 3
Database Link	Entrez Gene 1131 Human UniProt ID P20309
Background	Muscarinic acetylcholine receptor 3 is an Acetylcholine Receptor that controls smooth muscle contraction by mediating phosphoinositide hydrolysis and Ca2+ mobilization. Activation of this receptor causes secretion in glandular tissues. Mouse studies suggest that the M3 receptor may play a role in appetite stimulation and food intake.
Synonyms	CHRM3
Reference Data

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