Iba1 (AIF1) (149-161) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 0.3 - 1 µg/ml.
Reactivity	Hamster, Human, Monkey, Mouse, Porcine, Rat, Bovine, Equine, Goat, Rabbit
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from C-terminus of Human AIF1 (NP_116573.1; NP_001614.3).  Epitope: aa 149-161
Specificity	This antibody recognizes Allograft Inflammatory Factor-1 (AIF1) at aa 149-161. The antibody is expected to recognize isoform 1 (NP_116573.1) and isoform 3 (NP_001614.3).
Formulation	Tris saline buffer, pH ~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing.
Gene Name	allograft inflammatory factor 1
Database Link	Entrez Gene 199 Human UniProt ID P55008
Background	Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with chronic inflammatory processes. AIF1 is expressed by activated monocytes and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts.
Synonyms	AIF-1, Protein G1, IBA1, Allograft inflammatory factor 1
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.