DIXDC1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/16000. Western blot: Approx 120kDa band observed in Mouse and Rat Skeletal Muscle lysates (calculated MW of 132kDa according to Mouse NP_080477.1 and Rat NP_001102005.1). Recommended concentration: 1 - 3 µg/ml. An additional band of unknown identity was also consistently observed at 33kDa. This band was successfully blocked by incubation with the immunizing peptide.
Reactivity	Bovine, Canine, Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence RYCKERPSKDKE, from the internal region (near C-Terminus) of the protein sequence according to NP_060707.2.
Specificity	This antibody reacts to CCAR1.
Formulation	Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	DIX domain containing 1
Database Link	Entrez Gene 85458 Human UniProt ID Q155Q3
Background	DIXDC1 belongs to the DIXDC1 family and contains 1 CH (calponin homology) domain and 1 DIX domain. The coiled coil domain mediates interaction with MAP3K4 and inhibition of AXIN1 mediated JNK activation through MAP3K4. The DIX domain mediates interaction with AXIN1 and inhibition of AXIN1 mediated JNK activation through MAP3K1. Probably also mediates interaction with DVL2.
Synonyms	DIXDC1, CCD1, KIAA1735, DIX1
Reference Data

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