FRAT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA 1:1,000. Western blot 1:50 - 1:100. Immunohistochemistry 1:10 - 1:50´.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FRAT1.
Specificity	This antibody detects FRAT1 at Center.
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	frequently rearranged in advanced T-cell lymphomas 1
Database Link	Entrez Gene 10023 Human UniProt ID Q92837
Background	FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Synonyms	FRAT-1
Note	Molecular weight: 29093 Da
Reference Data

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