Collagen IV (COL4A2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/1000. Immunohistochemistry on paraffin sections: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Specificity	This antibody detects endogenous levels of COL4A2 protein. (region surrounding Pro175)
Formulation	PBS, pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.02% sodium azide, 50% glycerol
Concentration	1.0 mg/ml
Purification	Affinity chromatography (> 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~150 kDa
Gene Name	collagen type IV alpha 2
Database Link	Entrez Gene 1284 Human UniProt ID P08572
Background	The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (Types I, II, III and V) and basement membrane collagens (Type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.
Synonyms	COL4A2
Reference Data
Protein Families	Transmembrane
Protein Pathways	ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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