PKC theta (PRKCQ) pSer676 Rabbit Polyclonal Antibody

CAT#: AP20801PU-N

PKC theta (PRKCQ) pSer676 rabbit polyclonal antibody, Aff - Purified



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CNY 1,999.00

CNY 4,437.00


货期*
2周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution Western blot: 1/500 - 1/1000.
Immunohistochemistry on paraffin sections: 1/50 - 1/200.
Immunofluorescence: 1/50 - 1/200.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Specificity This antibody detects endogenous levels of PKC theta protein only when phosphorylated at Ser676.
Formulation Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity chromatography (> 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 80 kDa
Gene Name protein kinase C theta
Background Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (alpha, betaI, betaII, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, my and ny). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies.
Synonyms PKC theta, PKC-theta, nPKC-theta, Protein kinase C theta type
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, T cell receptor signaling pathway, Tight junction, Vascular smooth muscle contraction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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