Cytochrome P450 26B (CYP26B1) (418-430) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Canine, Human, Mouse, Rat, Equine, Hamster, Monkey, Rabbit
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of human CYP26B1
Specificity	This antibody reacts to the internal region of CYP26B1.
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purfied Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	cytochrome P450 family 26 subfamily B member 1
Database Link	Entrez Gene 232174 MouseEntrez Gene 312495 RatEntrez Gene 56603 Human UniProt ID Q9NR63
Background	Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Esential for postnatal survival.
Synonyms	CYP26A2, Cytochrome P450RAI2, Cytochrome P450 26B1, Cytochrome P450 26A2
Reference Data
Protein Families	Druggable Genome, P450
Protein Pathways	Retinol metabolism

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