FH (176-189) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/64000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. Western Blot.
Reactivity	Canine, Human, Mouse, Rat, Bovine, Chicken, Drosophila, Equine, Hamster, Insect, Monkey, Porcine, Sheep, Xenopus, Zebrafish
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of human FH
Specificity	This antibdoy reacts to the internal region of FH.
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purfied Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	fumarate hydratase
Database Link	Entrez Gene 24368 RatEntrez Gene 14193 MouseEntrez Gene 2271 Human UniProt ID P07954
Background	FH / Fumarase / MCL is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm.
Synonyms	HLRCC, LRCC, MCL, MCUL1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma

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