CD31 (PECAM1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA: 1/20000. Immunofluorescence: 1/100 - 1/500. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide from Human PECAM-1. Epitope: C-Terminus.
Specificity	This antibody detects endogenous levels of total PECAM-1 protein.
Formulation	PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Immunoaffinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	platelet and endothelial cell adhesion molecule 1
Database Link	Entrez Gene 18613 MouseEntrez Gene 5175 Human UniProt ID P16284
Background	CD31 (PECAM1) is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31 is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Synonyms	PECAM-1, EndoCAM, GPIIA'
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

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