Complement C5 (C5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: 1/2000 - 1/3000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Rabbit Anti-Human C5a polyclonal antibody is prepared by immunizing New Zealand white rabbits with human C5a antigen and isolating the C5a antibody from rabbit serum.
Formulation	PBS containing 0.02% sodium azide (NaN3) as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	complement component 5
Database Link	Entrez Gene 727 Human UniProt ID P01031
Background	Human C5a is 74 amino acids long and is a potent anaphylatoxin and chemotactic factor that stimulates directed migration of neutrophils, eosinophils, basophils and monocytes. Of all of the anaphylatoxic peptides generated by the activation of the complement system, C5a elicits the broadest range of activity. This activity includes the degranulation of mast cells and basophils, increased vascular permeability and the induction of cytokine synthesis by leukocytes.
Synonyms	Complement C5 alpha chain, C5a anaphylatoxin, CPAMD4
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

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