GAD67 (GAD1) Chicken Polyclonal Antibody

CAT#: AP31805PU-N

GAD67 (GAD1) chicken polyclonal antibody, Aff - Purified



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CNY 7,688.00


货期*
5周

规格
    • 100 ug

Cited in 1 publication.

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution Western Blot.
Immunocytochemistry.
Immunohistochemistry.
Recommended Dilutions:
1/2000-1/5000 for Western blots.
1/1000-1/2000 for Immunohistochemistry and Immunocytochemistry using 2% paraformaldehyde-fixed tissues or cells.
Quality Control: This antibody was analyzed by Immunohistochemistry (at a concentration of 1 µg/ml) using Fluorescein-labeled Goat anti-Chicken IgY (1/500 dilution, Cat.-No AP31795FC-N) as the secondary reagent.
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Immunogen Synthetic peptide KLH conjugated corresponding to a region near the C-terminus of this gene product, and was 100% conserved between the Human (Q99259), Mouse (P48318) and Rat (NP_058703) gene products.
After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity purified using a peptide column.
Specificity Recognizes Glutamic Acid Decarboxylase (GAD1/GAD67).
Formulation 10mM PBS (0.9%, w/v), pH 7.2 containing 0.02% Sodium Azide as preservative.
State: Aff - Purified
State: Liquid purified (0.45 µm filter sterilized) IgY fraction.
Concentration lot specific
Purification Affinity Chromatography using a peptide column.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted in the dark at 2-8°C.
Gene Name glutamate decarboxylase 1
Background Human Glutamic Acid Decarboxylase (GAD-67), [EC 4.1.1.15] is a 66,987 dalton protein (594 amino acids) selectively expressed in a subpopulation of GABAergic neurons of the CNS. It catalyzes the decarboxylation of glutamic acid, forming the inhibitory neurotransmitter β-amino butyric acid (GABA). It is also know as GAD-1.
Synonyms Glutamate decarboxylase 1, GAD-67
Reference Data
Protein Families Druggable Genome
Protein Pathways Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Butanoate metabolism, Metabolic pathways, Taurine and hypotaurine metabolism, Type I diabetes mellitus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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