PKM2 (PKM) (N-term) Rabbit Polyclonal Antibody
CAT#: AP53318PU-N
PKM2 (PKM) (N-term) rabbit polyclonal antibody, Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommend Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 123~153 amino acids from the N-terminal region of Human PKM2. |
Specificity | This antibody recognizes Human PKM2 (N-term). |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | pyruvate kinase, muscle |
Database Link | |
Background | PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. |
Synonyms | PK2, PK3, PKM, CTHBP, M2-PK, THBP1, OIP3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase M1/M2, Pyruvate kinase muscle |
Note | Molecular Weight: 57937 Da |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Glycolysis / Gluconeogenesis, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus |
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