Wilms Tumor Protein (WT1) (Center) Rabbit Polyclonal Antibody

CAT#: AP54572PU-N

Wilms Tumor Protein (WT1) (Center) rabbit polyclonal antibody, Aff - Purified



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

Cited in 1 publication.

Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution ELISA: 1:1;000.
Western blot: 1:100~500.
Immunohistochemistry on paraffin sections: 1:50~100.
Immunofluorescence: 1:10~50.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 353-383 (E361) amino acids from the Central region of human WT1
Specificity This antibody detects Wilms tumor protein (Center).
Formulation PBS with 0.09% (W/V) sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein A column followed by peptide affinity purification
Conjugation Unconjugated
Storage Condition Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name Wilms tumor 1
Background This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].
Synonyms WT33
Note Molecular Weight: 49188 Da
Reference Data
Protein Families Druggable Genome, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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