Cystatin C (CST3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA.  Western Blot: 1/200-1/2000.  Immunohistochemistry: 1/50-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from C-terminal domain of Human CYTC
Specificity	Reacts with Human 15 kDa CST3 protein.
Formulation	0.1M Tris 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	cystatin C
Database Link	Entrez Gene 1471 Human UniProt ID P01034
Background	Cystatin C is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells.Changes in cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
Synonyms	Cystatin C, Cystatin-3, CST3
Reference Data

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