MEK3 (MAP2K3) pThr222 Rabbit Polyclonal Antibody

CAT#: AP55763PU-S

MEK3 (MAP2K3) pThr222 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Western blot: 1:500~1:1000.
Immunohistochemistry on paraffin sections: 1:50~1:100.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of threonine 222(A-K-T(p)-M-D) derived from Human MAP2K3 (KLH-conjugated)
Specificity The antibody detects endogenous levels of MAP2K3 only when phosphorylated at threonine 222.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Condition Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Predicted Protein Size 39 kDa
Gene Name mitogen-activated protein kinase kinase 3
Background The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells.
Synonyms MAPKK 3, MEK3, MKK3, MAP kinase kinase 3
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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