Mouse Monoclonal Antibody [Clone ID: HCMV37]

Specifications

Product Data
Clone Name	HCMV37
Applications	ELISA, IF, IHC, Neutralize
Recommend Dilution	ELISA.  Immunofluorescence: Reactive only in acetone fixed CMV infected cells or frozen sections.
Reactivity	Cytomegalovirus
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CMV extracts.
Specificity	The antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen. Reacts with MRC-5 infected cells but not uninfected cells. This antibody has been found to be Neutralizing.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID P06473
Background	Human Cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB. Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for CMV mediated membrane fusion along with the gH/gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, wit a MW of approximately 100 kDa.
Synonyms	HCMV, HHV5, Glycoprotein B, UL55, Cytomegalovirus
Reference Data

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