Rabies Virus Mouse Monoclonal Antibody [Clone ID: Rab-50]

Specifications

Product Data
Clone Name	Rab-50
Applications	ELISA, FN, IF, WB
Recommend Dilution	ELISA. Immunofluorescence. Functional Assays. Western Blotting.
Reactivity	Rabies Lyssavirus
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified virions of SAD-Vnukova strain followed by Pitman-Moore strain. Spleen cells from immunised Balb/c female mice were fused with cells of the NSO myeloma cell line.
Specificity	This Rabies Virus Antibody clone Rab-50 shows conformation dependent specificity for the viral envelope glycoprotein. Not known to react with any other organism.
Formulation	PBS State: Purified State: Liquid Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Fractionation
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
Reference Data

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