IGF1 Mouse Monoclonal Antibody [Clone ID: BM23]

Specifications

Product Data
Clone Name	BM23
Applications	ELISA, IHC, R
Recommend Dilution	RIA. ELISA. Immunohistochemistry on Frozen Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human IGF-1 conjugated to ovalbumin.
Specificity	The basic IGF-1-like forms (pI>9.0) showed substantial cross-reactivity, as did Rat and Mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in-vitro bioassays for insulin-like, mitogenic and sulphation activities. Cross-reactivity: ILGF-1: 100% ILGF-2: 1% Proinsulin: 1.4% MSF: 1% Insulin: < 0.1%.
Formulation	PBS buffer with 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	insulin like growth factor 1
Database Link	Entrez Gene 3479 Human UniProt ID P05019
Background	Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.
Synonyms	IGF-I, Somatomedin-C, Mechano growth factor, MGF, IBP1
Reference Data

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