SCF (KITLG) Mouse Monoclonal Antibody [Clone ID: hKL12]

CAT#: BM4117

SCF (KITLG) mouse monoclonal antibody, clone hKL12, Purified



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CNY 9,994.00


货期*
5周

规格
    • 200 ug

Product images

Specifications

Product Data
Clone Name hKL12
Applications ELISA, IHC, WB
Recommend Dilution ELISA: 0.15 µg/ml as a titer in ELISA against the recombinant antigen.
Has been described to work in Wetsern blots and Immunohistochemistry.
Reactivity Human, Primate
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human stem cell factor.
Specificity This Monoclonal antibody hKL12 is specific for Stem Cell Factor (hSCF). hKL12 is useful for the detection of hSCF in tissues, isolated cells and for studying biological effects of Human Stem Cell Factor in vitro.
Antigen distribution on Tissue sections: Bone marrow stromal cells, fibroblasts, and fetal liver cells express SCF. Keratinocytes stain positive.
Formulation PBS, pH 7.2 containing 0.09% Sodium Azide as preservative
State: Purified
State: Lyophilized purified Ig fraction
Reconstitution Method Restore by adding 0.5 ml distilled water.
Concentration 0.4 mg/ml (after reconstitution)
Purification Affinity Chromatography
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name KIT ligand
Background SCF is a transmembrane protein expressed as two alternatively spliced isoforms, either 220 or 248 amino acids, the former lacking a peptidase cleavage site. The cleavage site is responsible for the release of the soluble form of the protein from the cell surface. The first 164 or 165 residues of the extracellular domain comprise soluble SCF, which exists in solution as a noncovalently linked homodimer. Alone, SCF is a weakly proliferative stimulus but acts synergistically with numerous cytokines. SCF is important in germ cell developement, and an indispensable facor for mast cell proliferation an differentiation.
Synonyms KITL, Kit ligand, c-Kit ligand, Stem cell factor, Mast cell growth factor, MGF
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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